Trisodium citrate

Trisodium citrate

Trisodium citrate has the chemical formula of Na₃C₆H₅O₇. It is sometimes referred to simply as “sodium citrate” and uses as food additives.

CAS NO:6132-04-3

E NO: E331iii

  • Description
  • Analysis


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Trisodium citrate

CAS NO:6132-04-3

E NO: E331iii

It is in the form of a white crystalline powder that has a salty and sour taste. It is a weak base and is used in combination with citric acid to produce biological buffers.Trisodium citrate that some times simply known as sodium citrate is a three sodium salts of citric acid.


This product  occurs as white, granular crystals or as white, crystalline powder. It is freely soluble in water and practically insoluble in ethanol (96 %).

Chemical formulaNa3c6h5o7
IUPAC nametrisodium;2-hydroxypropane-1,2,3-tricarboxylate;dihydrate
Molar mass258.06 g/mol (anhydrous), 294.10 g/mol (dihydrate)
appearanceWhite crystalline powder
Density1.7 g/cm3
Melting point> 300 °C (572 °F; 573 K) (hydrates lose water ca. 150 °C)
Boling pointDecomposes
Solubility in waterPentahydrate form: 92 g/100 g H2O (25 °C)


Chemical structure


Sodium citrate can be simply prepared by the acid-base reaction of sodium hydrogencarbonate (NaHCO3) and citric acid (C6H8O7)  according to the below reaction:

3NaHCO3 (aq) + C6H8O7 (aq) → Na3C6H5O7 (aq) + 3H2O (l) + 3CO2 (g)

Heat the solution until it reaches boiling point and until the excess water evaporates to form a precipitate and the sodium citrate product crystallizes. The filter product is then washed and dried.


Risk Assessment

SubstanceHazard information
Sodium hydrogencarbonateReleases carbon dioxide by gentle heating (or by acids). Sodium hydrogen carbonate is an approved food additive, E500, and is used as a baking soda.
Citric acidIt can cause severe eye and skin irritation and may cause respiratory irritation.

This is a valid food additive, E330.

Sodium citrateLow Hazard

Sodium citrate is an approved food additive, E331.




Trisodium citrate uses as acidity regulator, emulsifier, stabilizer. in food industry it used as a food additive that uses in heat treated butter milk and many other food products.

It is used as a weak acid conjugate base as a buffer or acidity regulator and can withstand pH changes. This property is used to control the acidity of some ingredients such as gelatinous desserts. It is also used in many dairy products to control acidity.

Several applications of sodium citrate as mention as below:


Baby Food, Infant Formula

Cereals, Snacks



Ready Meals, Instant Food

Sauces, Dressings, Seasonings


Buffering agent

Chelating agent


Clinical Nutrition

OTC, Food Supplements

Pharmaceutical Products

 Cleaners & Detergents

Dish Washing

Industrial Cleaners

Laundry Care

Surface Care

Personal Care


Oral Care


Instant Drinks, Syrups

RTD Tea and Coffee

Side effect

Side effects of overdose include muscle cramps, swelling, weakness, mood swings, rapid and shallow breathing, rapid heartbeat, black or bloody stools, severe diarrhea with seizures.